Ageing and gastrointestinal sensory function: altered colonic mechanosensory and chemosensory function in the aged mouse

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Ageing and gastrointestinal sensory function: altered colonic mechanosensory and chemosensory function in the aged mouse

KEY POINTS Remarkably little is known about how age affects the sensory signalling pathways in the gastrointestinal tract despite age-related gastrointestinal dysfunction being a prime cause of morbidity amongst the elderly population High-threshold gastrointestinal sensory nerves play a key role in signalling distressing information from the gut to the brain. We found that ageing is associated...

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ژورنال

عنوان ژورنال: The Journal of Physiology

سال: 2016

ISSN: 0022-3751

DOI: 10.1113/jp271403